Clinical Formulation
HPLC-verified · 60 caps/bottle · 3-bottle protocol
PAG NAD CORE™
If creams worked, you wouldn’t be here. The cellular approach to younger-looking skin — from within.
Inspired by the East Asian skin-longevity pattern. PAG NAD CORE™ targets the cellular conditions behind youthful-looking skin structure — from within, before the drift becomes visible. Not a cream. Not a surface treatment. A 90-day biological reset.
If you've tried creams, serums, and treatments without lasting results — it's not that they don't work on you. They can't work on anyone. Your skin blocks molecules over 500 Daltons at the surface. Collagen is 300,000. The only way to actually change what's happening is to work from the inside, targeting the three cellular failures driving visible aging simultaneously.
One commitment. Three months. One decision to make.
Why creams can't reach thisBaby skin biology
The East Asian skin advantage is biochemical, not cosmetic.
The baby skin look associated with many East Asian aging patterns is not simply a cream effect. It reflects a deeper cellular state: lower collagenase pressure, better matrix preservation, reduced glycation burden, and stronger sirtuin signaling.
PAG NAD CORE™ recreates those conditions from within: NAD+ for sirtuin signaling, Quercetin for senescent-cell cleanup, and Resveratrol for glycation control during the rebuilding window.
Creams stop at the surface
A moisturizer can improve glow. It cannot rebuild the dermal environment.
The 500 Dalton Rule
Creams are blocked by physics
Your skin's outer layer blocks molecules over 500 Daltons. Collagen is 300,000 Da. Most serums exceed 1,000 Da. 99% of topical products never reach the dermis, where real aging happens.
MMP-1 Collagenase
The real culprit is enzymatic
MMP-1 collagenase cuts through collagen fibers like molecular scissors — triggered by UV, stress, and sugar. No cream can deactivate this pathway. You need systemic intervention.
Cellular Energy Crisis
NAD+ depletion drives aging
NAD+ levels drop 50% between age 20 and 60. Without it, sirtuin signaling collapses, cellular repair slows, and the dermal matrix can't maintain its youthful architecture.
Complete formulation
Three compounds. Three failure modes. One protocol.
Supplement Facts
Serving size: 2 capsules · Servings per container: 30Other ingredients: HPMC vegetable capsule, Microcrystalline Cellulose, Brown Rice Flour, Olive Oil, Silicon Dioxide, Magnesium Stearate (vegetable source). Free from: heavy metals · GMO · artificial binders · gluten.
"Baby skin is not a surface finish. It is a cellular state: low collagenase pressure, clean fibroblast signaling, and collagen that can stay flexible."
The molecular stack
How each compound translates the Asian skin-longevity pattern.
NAD+
The central cofactor for cellular energy metabolism and sirtuin activity. NAD+ levels drop ~50% between age 20–60. Restoring them reactivates SIRT1/SIRT3 signaling — which regulates stress response, inflammatory transcription, and MMP-1 collagenase pressure on the dermal matrix. Delivered as Nicotinamide Riboside (NR), a precursor with high oral bioavailability that significantly raises intracellular NAD+ levels.
Quercetin
A senolytic polyphenol that supports clearance of senescent "zombie" fibroblasts. These damaged cells release SASP — the inflammatory secretome that accelerates collagen breakdown. Quercetin reduces the burden that makes skin age from the inside out.
Resveratrol
A SIRT1-activating polyphenol with direct glycation-control relevance. Glycation — the cross-linking of collagen fibers by sugar — stiffens and degrades the matrix as it forms. Resveratrol protects the quality of newly synthesized collagen during the 90-day rebuilding window.
The protocol structure
Why 90 days — and what happens inside them.
Skin does not renew in a week. The biological processes targeted here operate on a timeline of months. The 90-day structure matches that biological reality — not arbitrary marketing.
3 bottles. 90 days. One structured protocol designed to matter.
Arrest
NAD+ restoration supports SIRT1/SIRT3 signaling and begins reducing MMP-1 collagenase pressure. Senescent fibroblast clearance starts. The cellular environment stabilizes.
Rebuild
Healthy fibroblasts restart Type I and III collagen output. Texture and elasticity changes begin to appear. Photos start feeling less harsh for most users.
Integrate
New collagen matures into stable architecture. Resveratrol protects quality from glycation. The compounding effect of 3 months becomes visible — skin that looks more supported, more rested, more like itself.
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What 90 days actually feels like.
Everything required for the complete cycle
Designed as a full 90-day allocation because collagen breakdown, fibroblast output, and matrix integration do not complete in a 30-day cosmetic window.
Frequently asked
Your questions, answered.
It's a fair question. The supplement industry is full of underdosed formulas, vague claims, and ingredients chosen for marketing rather than biology. Your skepticism is earned. Here's what distinguishes PAG NAD CORE™: every ingredient is dosed at amounts used in peer-reviewed research (not trace amounts for label decoration), purity is HPLC-verified at ≥98% per batch, and the formulation addresses three distinct pathways simultaneously rather than stacking one popular compound. We can't guarantee results for everyone — no honest brand can. What we can guarantee is that if you complete the full 90 days and don't see a visible difference, we refund the entire purchase. No loops to jump through.
Most users begin noticing changes in skin texture and how rested their face looks during Phase 2 (days 31–60). The most meaningful structural changes — bounce, density, reduced puffiness in photos — appear by the end of the full 90-day cycle. Collagen biology operates on weeks-to-months timelines; this protocol is calibrated to match it.
Yes. PAG NAD CORE™ works internally and does not interfere with topical routines. In fact, improving the internal cellular environment can make your topical products perform better — healthier skin cells respond more effectively to hydration and surface treatments.
No. The biological pathways targeted — NAD+ / SIRT1 signaling, senescent cell clearance, collagen matrix maintenance — are universal. The marketing language reflects the demographic most focused on this outcome, but the formulation is designed for any adult experiencing the biological effects of age on skin quality.
Most NAD+ supplements are positioned for energy or general longevity. PAG NAD CORE™ is specifically formulated as a dermal protocol — pairing NAD+ (as highly bioavailable Nicotinamide Riboside) with a senolytic (Quercetin) and a SIRT1 activator (Resveratrol) at clinically relevant doses. This multi-pathway approach targets the three distinct failure modes driving visible skin aging simultaneously.
NAD+ (NR), Quercetin, and Resveratrol are generally well-tolerated at these doses. Quercetin can occasionally cause mild digestive sensitivity when taken without food — taking with a meal avoids this. As with any supplement, consult your healthcare professional if you are pregnant, nursing, taking medication, or have a medical condition.
Complete the full 90-day protocol as directed. If you do not observe measurable visible improvement in your skin's structure, density, or overall quality, contact us for a full refund. We ask only that you give the protocol its full duration — results require consistency, not occasional use.