PAG LABS Research Library
Evidence-first explainers on skin aging, photoaging, collagen, cellular senescence, NAD+ biology, quercetin and resveratrol. Human outcomes, biomarkers, mechanisms and preclinical evidence are labeled separately.
Sep 08, 2026
Photoaging and intrinsic aging overlap, but they are not the same process. Learn how UV exposure changes collagen, pigmentation and skin structure—...
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Jun 06, 2026
Creams are not useless and oral supplements are not automatically deeper. Compare sunscreen, retinoids, moisturizers and oral interventions by rout...
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Jun 06, 2026
A technical but readable guide to UV-induced MMP-1, collagen fragmentation and why mechanistic pathways should not be converted into untested suppl...
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Jun 06, 2026
Resveratrol has extensive mechanistic skin research, but oral anti-wrinkle claims are ahead of the evidence. Here is what reviews actually support.
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Jun 06, 2026
Prevention and correction are not “Asian vs Western” biology. This guide compares photoprotection, barrier care, retinoids and procedures without c...
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Jun 06, 2026
There is no universal 90-day collagen clock. This guide explains why skin remodeling is slow, how trial timelines vary and what a 90-day supplement...
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Jun 06, 2026
Quercetin is widely called a natural senolytic, but the human evidence is more specific: early trials used dasatinib plus high-dose quercetin, not ...
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Jun 06, 2026
The 500 Dalton rule is a useful skin-penetration heuristic—not proof that creams do not work. Here is what molecular size, formulation and clinical...
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Jun 06, 2026
A direct comparison of oral collagen and NAD+ research, separating visible human skin outcomes from biomarker and mechanistic evidence.
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Jun 06, 2026
A precise guide to NAD+ and skin aging that separates direct NAD+ from NR and NMN studies and distinguishes biomarkers from visible skin outcomes.
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Jun 06, 2026
A transparent ranking of popular skin-aging supplements by direct human skin evidence—not by mechanism, hype or brand preference.
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Jun 06, 2026
Why skin-aging patterns can differ across populations—and why ethnicity, diet or Okinawan longevity should not be turned into simplistic wrinkle cl...
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500 mg NAD+, 250 mg quercetin dihydrate extract and 150 mg Japanese knotweed extract standardized to 98% resveratrol per 2-capsule serving.
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