NAD+ helps reactions that convert nutrients into usable cellular energy.
Made in the USA
3 bottles · 90 daily servings
90-Day Satisfaction
Guarantee under published refund terms
No Subscription
One purchase · no auto-billing
Exact-Label Formula
No proprietary blend
One bottle shown. Your protocol includes 3 bottles · 180 capsules.
NAD+ supplement for skin longevity
PAG NAD CORE™
The NAD+ Skin Protocol.
500 mg direct NAD+ with quercetin and resveratrol — a 90-day supplement protocol built around the cellular biology researchers study in skin aging.
500 mgdirect NAD+
2capsules daily
90daily servings
0subscriptions
Your daily protocol
$2per day
$180 one-time total
3 bottles · 90 daily servings · no subscription
✓
90-Day Satisfaction Guarantee. See terms.
US standard shipping: free · International shipping: $25 flat
After dispatch: US 3–7 business days · Canada 3–5 · UK/EU 4–7 · Australia, New Zealand & APAC 6–10 · other available destinations 7–14. Processing: 1–3 business days. Shipping details.
See what NAD+ does in skin biology ↓After dispatch: US 3–7 business days · Canada 3–5 · UK/EU 4–7 · Australia, New Zealand & APAC 6–10 · other available destinations 7–14. Processing: 1–3 business days. Shipping details.
The 10-second NAD+ skin story
Skin aging does not begin at the surface.
Every living skin cell must make energy, coordinate stress responses and maintain tissue. NAD+ is a coenzyme inside that machinery. PAG NAD CORE supplies 500 mg direct NAD+ with quercetin and resveratrol in one daily protocol.
NAD+cellular coenzyme
PARP enzymes consume NAD+ while coordinating cellular responses to DNA damage.
Sirtuins use NAD+ in pathways researchers connect with stress response and aging biology.
A human tissue study associated older age with lower NAD+ levels in skin samples.
Biological context: Massudi et al., 2012 · PAG LABS NAD+ & skin research note
8
weeks · human signal
A human study. A hard-to-ignore question.
Six of seven skin self-assessments improved.
In a 2022 Japanese study, 16 postmenopausal women completed eight weeks of 300 mg NMN daily. Participants reported improvement across six of seven skin questions, including perceived moisture, dryness and firmness. The breakout item did not improve.
6 improved self-assessments · 1 did not
The human signal
Skin moisture, dryness and firmness entered a real eight-week NAD+ precursor study.
The useful distinction
The study used NMN. PAG NAD CORE contains direct NAD+.
Outside the lab
Skin keeps entering the conversation.
We reviewed public NAD-precursor experiences. Here are 15 positive skin observations people chose to report—in their own routines, on their own timelines.
Other people noticed first.
One creator said compliments about his skin came before he personally noticed a change.
View the public reportSmoother. More hydrated.
One NMN user described skin that felt smoother and more hydrated, alongside other changes in routine and lifestyle.
View the public reportA little smoother by month four.
A 42-year-old NMN user said his skin appeared smoother after four months of a consistent routine.
View the public reportHealthier-looking skin.
One commenter listed healthier-looking skin among the changes noticed after adding NMN to a broader supplement routine.
View the public reportSkin spots stood out first.
An NMN user over 50 said changes in skin spots became the most noticeable difference at around six weeks.
View the public reportSofter skin.
In a later NMN update, one user described skin that had become somewhat softer, alongside faster-looking hair and nail growth.
View the public reportBetter skin. Younger-looking.
After a year with NMN, a 47-year-old said his skin looked much better and that he felt and looked younger.
View the public reportMore supple. Less dry.
A 68-year-old described more supple skin and less dryness and flaking while discussing NR and NMN experiences.
View the public reportSmoother texture. More even.
Another person in the same discussion reported smoother texture, a more even appearance and less-prominent deeper lines.
View the public reportHair, skin and nails stood out.
A long-term NAD-precursor user said changes in hair, skin and nails were among the benefits noticed over time.
View the public reportSkin entered the results.
While discussing upcoming NMN skin trials, one user said better skin was among the changes personally noticed.
View the public reportLess crepey over time.
A 63-year-old said comparison photos suggested the skin on the arms and legs looked less crepey over time.
View the public reportSofter skin came early.
A 32-year-old with sensitive skin and rosacea said the skin felt softer within the first two weeks of NMN use.
View the public reportStill wrinkle-free at 50.
One long-term NMN user said the skin was doing better and remained wrinkle-free at 50, with people often guessing a younger age.
View the public reportSmoother in a broader routine.
A 49-year-old said NMN helped parts of his skin look smoother while also using collagen, retinol, red light and sun protection.
View the public reportIndependent signal:These public reports concern NMN or NR, are independent of PAG LABS and are not PAG NAD CORE customer reviews.
The protocol, made simple
Three bottles. One daily cue. Ninety days to form your own view.
The promise here is practical: the complete routine is already on your shelf. No mid-protocol reorder, no subscription and no automatic renewal.
Build the cue.
Take the labeled two-capsule serving at the same point in your day.
Keep it uninterrupted.
Your second bottle is ready. Continue the routine without placing another order.
Make your own comparison.
Finish the planned supply. If you track photos, keep the lighting and angle consistent.
$180 once. 90 days. About $2 a day.3 bottles · 180 capsules · no subscription
Start my 90-day protocolUS shipping free · International shipping $25 flat
The idea behind PAG LABS
The mirror shows the surface. Skin longevity starts below it.
Fine lines. A drier feel. Skin that seems slower to bounce back. Most beauty routines answer with another product for the surface. PAG LABS asks what is happening in the living tissue beneath it.
That question led us from visible aging patterns to the cellular systems skin uses for energy, stress response and repair. NAD+ sits inside that biology.
PAG NAD CORE brings direct NAD+, quercetin and resveratrol into one daily supplement. Three disclosed ingredients. Two capsules. Ninety days already on your shelf.
The Japanese skin-aging clue
A visible difference opened a deeper question.
In a 2004 comparison, researchers studied 70 Japanese women in Tokyo and 85 Caucasian women in Cincinnati, aged 20–69. They assessed wrinkles in eight facial areas and sagging below the cheekbone.
The Japanese participants had lower wrinkle scores in several areas, particularly the lower face. Sagging scores were higher in the Cincinnati group from age 40 onward. Read Tsukahara et al., 2004.
The study did not name one beauty secret. It revealed something more useful: visible skin aging follows patterns, and the biology below the surface deserves attention.
Human observation · Skin-aging research
What was actually measured?
155women in Tokyo and Cincinnati
8facial areas assessed for wrinkles
40+age groups with higher sagging scores in the Cincinnati participants
Population comparison, Tsukahara et al., 2004. These figures describe the study, not product results.
From observation to biology
Japanese research supplies the clue. NAD+ supplies the cellular question.
The Tokyo comparison does not make NAD+ the cause of the differences it measured. Genetics, pigmentation, environment, UV exposure and daily behavior all belong in that story.
It points us toward the better question: what does living skin need to keep doing its work? Energy metabolism. Barrier maintenance. Cellular responses to stress and DNA damage.
NAD+ is part of that machinery. PAG NAD CORE turns this research direction into a simple daily protocol with exact ingredient amounts you can inspect before buying.
01 · The molecule at the centre
Your skin is living tissue. NAD+ is part of its working machinery.
NAD+ is a coenzyme involved in the reactions that turn nutrients into usable cellular energy. Enzymes called PARPs use it in responses to DNA damage; sirtuins use it in cellular regulation.
In a human tissue study, researchers found an association between age and lower NAD+ levels in skin samples. That observation helps explain why the NAD system attracts attention in skin-aging research. Massudi et al., 2012.
Energy, repair and resilience are compelling research questions—not just beauty buzzwords. Our formula supplies 500 mg of direct NAD+ in a two-capsule serving, together with quercetin and a standardized resveratrol source.
An intriguing human signal
Eight weeks. A Japanese study. A skin question worth following.
In 2022, a Japanese research team followed 17 postmenopausal women taking 300 mg of NMN daily for eight weeks. Sixteen completed the study. Six of seven skin self-assessments improved, including perceived moisture, dryness and firmness; the breakout item did not.
It is an early signal, not a finished answer: this was a before-and-after study without a placebo, using NMN—a precursor of NAD+, not the direct NAD+ in PAG NAD CORE. Morita et al., 2022.
Alongside this human work, experimental studies explore NAD-related pathways in collagen preservation and skin-barrier function. That is the field we follow: specific molecules, specific findings, and a closer look at what skin needs.
02 + 03 · The plant compounds
Why pair NAD+ with quercetin and resveratrol?
We chose a focused formula around a cellular coenzyme and two plant polyphenols. Each has a distinct identity and its own research background. Here is what earns each one a place in the ingredient story.
Quercetin · 250 mg
Quercetin is a plant flavonoid investigated in experimental research on oxidative stress and cellular senescence—the state in which cells stop dividing and can change the signals they release.
That makes it an interesting subject in aging biology. Our formula provides 250 mg of quercetin dihydrate extract, sourced from Sophora japonica flower buds, per daily serving.
Resveratrol source · 150 mg extract
Resveratrol is a polyphenol investigated in skin-aging and cellular-signaling research. A review of skin studies describes a promising experimental field, spanning different models and applications. Hecker et al.
We use 150 mg of Japanese knotweed root extract, standardized to 98% resveratrol. The extract quantity and standardization are both printed on the label.
Know your formula
Read the amounts. Know the sources. Compare the formula.
With a supplement, the detail on the label is part of the decision. PAG NAD CORE discloses each active amount per two-capsule serving:
- Direct NAD+: 500 mg of nicotinamide adenine dinucleotide.
- Quercetin dihydrate extract: 250 mg, from Sophora japonica flower buds.
- Japanese knotweed root extract: 150 mg, standardized to 98% resveratrol.
Every bottle contains 60 capsules. There is no proprietary blend hiding the individual quantities. The product is made in the USA; “Japanese knotweed” identifies the botanical source.
Use those specifics when comparing another product: the same ingredient name alone does not tell you the serving amount, extract standardization or cost per day.
The part you can verify
Turn the bottle around.
No mystery blend. The active amounts, ingredient forms, serving size and directions are printed on the label so you can compare the formula before you buy.
How it fits into your life
Keep the skincare you love. Give your new habit a place.
PAG NAD CORE belongs with your daily supplement routine. Keep your cleanser, moisturizer and sun protection in their usual places. Choose a regular moment for your two capsules and follow the label directions.
The practical appeal is simple: the three selected ingredients are already combined. You have one bottle to reach for and one serving to remember.
And when that first bottle is finished, the second is ready. There is no monthly reorder to organize halfway through the routine.
Ninety days, already on your shelf.
Starting a habit is easy. Making it convenient to repeat is where the planning matters. The complete PAG NAD CORE offer includes three bottles, each with 60 capsules and 30 daily servings.
You receive 180 capsules for 90 days in a single order. Use the labeled serving of two capsules daily with 6 oz (177 ml) of water, or as directed by a healthcare professional.
Keep a simple record of your routine and your own experience. If you take photographs, use consistent lighting and angles. At the end of your supply, the next decision is yours.
No subscription. No automatic renewal. No cancellation to remember.
Is this your kind of routine?
A considered formula. A habit that takes seconds.
A useful routine should be simple enough to repeat. PAG NAD CORE combines a cellular coenzyme with two plant polyphenols in one two-capsule serving.
500 mg NAD+. 250 mg quercetin extract. 150 mg Japanese knotweed extract standardized to 98% resveratrol. Every amount is disclosed, so you can compare the formula without decoding a proprietary blend.
Your complete supply arrives in one order. Your second and third bottles are already there when you need them. No recurring payment, and no cancellation to remember.
Your complete supply
Make room for a daily habit.
Your complete order contains three bottles: 180 capsules and 90 daily servings of the same disclosed formula.
Take two capsules daily as directed. When the first bottle is finished, your next one is already on the shelf. You pay once, with no subscription or automatic renewal.
The 90-day satisfaction guarantee applies after completion of the program, under the refund terms below.
$2 per day
$180 one-time total
Add my 90-day supply3 bottles · 90 daily servings · no subscription
US shipping free · International shipping $25 flat
The NAD+ skin questions people actually ask.
Does NAD+ help skin?
NAD+ is part of the cellular machinery skin uses for energy metabolism, stress response and DNA-damage signaling. Human skin-tissue research has associated older age with lower NAD+ levels, while supplement studies on visible skin outcomes are still early. PAG NAD CORE provides direct NAD+ in a clearly disclosed daily formula.
What does NAD+ do in skin biology?
NAD+ participates in reactions that turn nutrients into usable cellular energy. PARP enzymes use it during responses to DNA damage, and sirtuins use it in cellular regulation. These mechanisms explain the research interest in NAD+ and skin longevity.
Is NAD+ better than collagen for skin?
They answer different questions. Collagen peptides have more direct human studies measuring hydration, elasticity and wrinkles, although study quality is debated. NAD+ research focuses more on cellular energy and stress-response biology. Some people may view them as complementary rather than substitutes.
How long does NAD+ take to work for skin?
There is no established timetable for a visible skin result from direct oral NAD+. The PAG protocol provides 90 daily servings so the routine is long enough to follow consistently and evaluate without a monthly reorder. Ninety days describes the supply, not a guaranteed result date.
Is the NAD+ in this formula NR or NMN?
It is direct NAD+—nicotinamide adenine dinucleotide—at 500 mg per serving. NR and NMN are different molecules used in much of the human precursor research. That distinction matters when comparing formulas and studies.
What am I actually buying?
A one-time purchase of three bottles of PAG NAD CORE. Each bottle contains 60 capsules and 30 servings. The complete offer provides 180 capsules and 90 daily servings.
Why order 90 days at once?
It gives you three consecutive 30-day supplies without a mid-protocol reorder. Your second and third bottles are already on the shelf, and there is no subscription or automatic renewal.
Can I keep my usual skincare?
Yes. PAG NAD CORE fits alongside a topical routine. Keep appropriate cleansing, moisturization and sun protection in place; the supplement addresses a different part of the skin-longevity conversation.
How does the 90-day guarantee work?
Complete the 90-day program, then submit an eligible refund request within 10 days of completion with your order number and a brief account of your experience. The guarantee is limited to one eligible order per customer. Read the full refund terms.
Will I be charged again?
No. This is a one-time purchase with no subscription or automatic renewal. Another supply is ordered only if you choose to place a new order.
Supplement facts, directions & precautions
A dietary supplement designed to support cellular energy production and overall healthy aging. Formulated to help maintain healthy levels of NAD+, a coenzyme involved in key metabolic and cellular processes, it’s commonly used in wellness routines focused on vitality, energy, and longevity. By supporting normal cellular function, it may help promote overall well-being and resilience as the body ages. Each capsule provides a convenient daily option for those looking to support long-term health, energy balance, and healthy aging as part of an active lifestyle.
Suggested use
As a dietary supplement,adults take two (2) capsules daily. For best results, take with 6-8 oz of water or as directedby a healthcare professional.
Warning
KEEP OUT OF THE REACH OF CHILDREN. DO NOT USE IF SAFETY SEAL IS DAMAGED OR MISSING. STORE IN A COOL, DRY PLACE.
Disclaimer
Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Your next daily habit starts here.
A question sparked by Japanese skin research. A formula built around NAD+ and two selected polyphenols. One serving to remember.
Choose your 90-day supply of PAG NAD CORE. Three bottles, ready from day one. Your next order stays your choice.
US shipping free · International shipping $25 flat
$2 per day
$180 total · 90 days · US free / Intl $25
Go deeper
Choose with the full picture.
90-Day Satisfaction Guarantee
Give the full protocol a fair test.
Complete the full 90-day program. If you are not satisfied, the current PAG LABS Refund Policy allows eligible customers to request a refund by contacting us within 10 days after the program ends. The request must include the order number and a brief description of the experience; the satisfaction guarantee applies to one eligible order per customer.
Read the Refund Policy