Jun 06, 2026
The 500 Dalton Rule: What It Really Means for Skincare
The 500 Dalton rule is a useful skin-penetration heuristic—not proof that creams do not work. Here is what molecular size, formulation and clinical...
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The Science
Evidence-first explainers on skin aging, photoaging, collagen, cellular senescence, NAD+ biology, quercetin and resveratrol. Human outcomes, biomarkers, mechanisms and preclinical evidence are labeled separately.
Research before product
See exactly what PAG NAD CORE contains.
500 mg NAD+, 250 mg quercetin dihydrate extract and 150 mg Japanese knotweed extract standardized to 98% resveratrol per 2-capsule serving.
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